NOI - Northwestern Orthopaedic Institute, Chicago
Northshore University HealthSystem
Knee Replacement, Chicago
 
NOI's Doctors
Adam W. Bennett
Victoria Anne Brander
Mark Bowen
Patrick Birmingham
Charles Carroll
Raju S. Ghate
Armen Kelikian
Steven A. Kodros
Srdjan Mirkovic
Gordon W. Nuber
Mark Nolden
Cherise Russo
S. David Stulberg
Richard L. Wixson
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NOI Specialty
Diagnostic Radiology
 
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Platelet Rich Plasma PRP Injections

Platelet-rich plasma or PRP is an "autologous blood therapy" that uses a patient's own blood components to stimulate a healing response in damaged tissues. In response to an injury or tissue damage, your body naturally recruits platelets and white blood cells from the blood to initiate a healing response. Under normal conditions, platelets store numerous growth factors which are released in response to signals from the injured tissue. Modern technology allows us to concentrate platelets and white blood cells from your blood, and induce this growth factor release as we inject the solution directly into injured tissue, simulating this same healing response in a more powerful form. By enhancing the body's natural healing capacity, the treatment may lead to a more rapid, more efficient, and more thorough restoration of the tissue to a healthy state.

To prepare PRP, a small amount of blood is taken from the patient. The blood is then placed in a centrifuge. The centrifuge spins and through a multi-functional process separates the plasma from the blood producing the PRP. This increases the concentration of platelets and growth factors up to 500% also increasing hMSC (human stem cells) proliferation as a function of 8-day exposure to platelet released concentrations 10x. (x= increase above native levels)

When PRP is injected into the damaged area it stimulates the tendon or ligament causing mild inflammation that triggers the healing cascade. As a result new collagen begins to develop. As this collagen matures it begins to shrink causing the tightening and strengthening of the tendons and ligaments of the damaged area.

 

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